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A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration

Regeneration depends on the ability of mature cells at the injury site to respond to injury, generating tissue-specific progenitors that incorporate the blastema and proliferate to reconstitute the original organ architecture. The metabolic microenvironment has been tightly connected to cell functio...

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Detalles Bibliográficos
Autores principales: Brandão, Ana S, Borbinha, Jorge, Pereira, Telmo, Brito, Patrícia H, Lourenço, Raquel, Bensimon-Brito, Anabela, Jacinto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395193/
https://www.ncbi.nlm.nih.gov/pubmed/35993337
http://dx.doi.org/10.7554/eLife.76987