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A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration
Regeneration depends on the ability of mature cells at the injury site to respond to injury, generating tissue-specific progenitors that incorporate the blastema and proliferate to reconstitute the original organ architecture. The metabolic microenvironment has been tightly connected to cell functio...
Autores principales: | Brandão, Ana S, Borbinha, Jorge, Pereira, Telmo, Brito, Patrícia H, Lourenço, Raquel, Bensimon-Brito, Anabela, Jacinto, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395193/ https://www.ncbi.nlm.nih.gov/pubmed/35993337 http://dx.doi.org/10.7554/eLife.76987 |
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