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A key F27I substitution within HCDR1 facilitates the rapid maturation of P2C-1F11-like neutralizing antibodies in a SARS-CoV-2-infected donor

Although thousands of anti-SARS-CoV-2 monoclonal neutralizing antibodies (nAbs) have been identified and well characterized, some crucial events in the development of these nAbs during viral infection remain unclear. Using deep sequencing, we explore the dynamics of antibody repertoire in a SARS-CoV...

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Detalles Bibliográficos
Autores principales: Wang, Miao, Fan, Qing, Zhou, Bing, Ye, Haocheng, Shen, Senlin, Yu, Jiazhen, Cheng, Lin, Ge, Xiangyang, Ju, Bin, Zhang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395280/
https://www.ncbi.nlm.nih.gov/pubmed/36057256
http://dx.doi.org/10.1016/j.celrep.2022.111335