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A key F27I substitution within HCDR1 facilitates the rapid maturation of P2C-1F11-like neutralizing antibodies in a SARS-CoV-2-infected donor
Although thousands of anti-SARS-CoV-2 monoclonal neutralizing antibodies (nAbs) have been identified and well characterized, some crucial events in the development of these nAbs during viral infection remain unclear. Using deep sequencing, we explore the dynamics of antibody repertoire in a SARS-CoV...
Autores principales: | Wang, Miao, Fan, Qing, Zhou, Bing, Ye, Haocheng, Shen, Senlin, Yu, Jiazhen, Cheng, Lin, Ge, Xiangyang, Ju, Bin, Zhang, Zheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395280/ https://www.ncbi.nlm.nih.gov/pubmed/36057256 http://dx.doi.org/10.1016/j.celrep.2022.111335 |
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