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The establishment of polypeptide PSMA‐targeted chimeric antigen receptor‐engineered natural killer cells for castration‐resistant prostate cancer and the induction of ferroptosis‐related cell death

BACKGROUND: The mortality of castration‐resistant prostate cancer (CRPC) is high due to lack of an effective treatment. Chimeric antigen receptor (CAR)‐based therapy is a promising immunotherapeutic strategy. Here, we aimed to design a novel CAR‐natural killer (NK) cells with a clinically significan...

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Detalles Bibliográficos
Autores principales: Wu, Liyuan, Liu, Fei, Yin, Le, Wang, Fangming, Shi, Hui, Zhao, Qinxin, Yang, Feiya, Chen, Dong, Dong, Xiying, Gu, Yuchun, Xing, Nianzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395313/
https://www.ncbi.nlm.nih.gov/pubmed/35706368
http://dx.doi.org/10.1002/cac2.12321