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The establishment of polypeptide PSMA‐targeted chimeric antigen receptor‐engineered natural killer cells for castration‐resistant prostate cancer and the induction of ferroptosis‐related cell death
BACKGROUND: The mortality of castration‐resistant prostate cancer (CRPC) is high due to lack of an effective treatment. Chimeric antigen receptor (CAR)‐based therapy is a promising immunotherapeutic strategy. Here, we aimed to design a novel CAR‐natural killer (NK) cells with a clinically significan...
Autores principales: | Wu, Liyuan, Liu, Fei, Yin, Le, Wang, Fangming, Shi, Hui, Zhao, Qinxin, Yang, Feiya, Chen, Dong, Dong, Xiying, Gu, Yuchun, Xing, Nianzeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395313/ https://www.ncbi.nlm.nih.gov/pubmed/35706368 http://dx.doi.org/10.1002/cac2.12321 |
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