Cargando…

Alpinumisoflavone ameliorates choroidal neovascularisation and fibrosis in age-related macular degeneration in in vitro and in vivo models

Age-related macular degeneration (AMD) is a major cause of vision loss in the elderly population. Anti-vascular endothelial growth factor (VEGF) antibody therapy is applicable to neovascularisation of AMD; however, the prevention of fibrosis after anti-VEGF monotherapy is an unmet medical need. Subr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Eunhye, Song, Yunjeong, Gu, Sun Mi, Jo, Yang Hee, Yeon, Sang Won, Han, Kyu Jin, Lee, Mi Kyeong, Min, Jung Kee, Yun, Jaesuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395367/ https://www.ncbi.nlm.nih.gov/pubmed/35995845 http://dx.doi.org/10.1038/s41598-022-18531-y

Ejemplares similares

Fractal analysis of polypoidal choroidal neovascularisation in age-related macular degeneration
por: Serra, Rita, et al.
Publicado: (2021)

Macular vortex vein with choroidal neovascularisation in pathologic myopia
por: Schouten, Ike M, et al.
Publicado: (2019)

Alpinumisoflavone
por: Harrison, Jerry Joe Ebow Kingsley, et al.
Publicado: (2008)

Anti-VEGF therapies in the treatment of choroidal neovascularisation secondary to non-age-related macular degeneration: a systematic review
por: Stuart, Arabella, et al.
Publicado: (2015)

Characterisation of macular neovascularisation subtypes in age-related macular degeneration to optimise treatment outcomes
por: Mathis, Thibaud, et al.
Publicado: (2022)

Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation
por: Fernández-Robredo, Patricia, et al.
Publicado: (2017)

Matrix Metalloproteinase 10 Contributes to Choroidal Neovascularisation
por: González-Zamora, Jorge, et al.
Publicado: (2022)

Is IL-10 a Good Target to Inhibit Choroidal Neovascularisation in Age-Related Macular Disease?
por: Lightman, Sue, et al.
Publicado: (2006)

Effect of Intravitreal Ranibizumab in the Treatment of Peripapillary Choroidal Neovascularisation
por: Hamoudi, Hassan, et al.
Publicado: (2011)

Myopic choroidal neovascularisation: current concepts and update on clinical management
por: Wong, Tien Y, et al.
Publicado: (2015)

Pilot study of ziv-aflibercept in myopic choroidal neovascularisation patients
por: Nawar, Amin E., et al.
Publicado: (2020)

Expression of purinergic receptors on microglia in the animal model of choroidal neovascularisation
por: Li, Lu, et al.
Publicado: (2021)

Biomarkers of macular neovascularisation activity using optical coherence tomography angiography in treated stable neovascular age related macular degeneration
por: Hanumunthadu, Daren, et al.
Publicado: (2023)

Aflibercept as primary treatment for myopic choroidal neovascularisation: a retrospective study
por: Bruè, C, et al.
Publicado: (2016)

Correlation of retinal alterations with vascular structure of macular neovascularisation in swept-source optical coherence tomography angiography in age-related macular degeneration
por: Faatz, Henrik, et al.
Publicado: (2022)

Development of a Deep-Learning-Based Artificial Intelligence Tool for Differential Diagnosis between Dry and Neovascular Age-Related Macular Degeneration
por: Heo, Tae-Young, et al.
Publicado: (2020)

Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series
por: Faes, Livia, et al.
Publicado: (2019)

Idiopathic Choroidal Neovascularisation as the Inaugural Sign of Multiple Evanescent White Dot Syndrome
por: Papadia, Marina, et al.
Publicado: (2010)

Recurrence risk of myopic choroidal neovascularisation: a systematic review of current study
por: Victor, Andi Arus, et al.
Publicado: (2023)

A Pharmacological Overview of Alpinumisoflavone, a Natural Prenylated Isoflavonoid
por: Ateba, Sylvin Benjamin, et al.
Publicado: (2019)

The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation
por: Zhang, Peipei, et al.
Publicado: (2021)

Age-related macular degeneration: choroidal ischaemia?
por: Coleman, D Jackson, et al.
Publicado: (2013)

Diagnostic accuracy of OCTA and OCT for myopic choroidal neovascularisation: a systematic review and meta-analysis
por: Ho, Sharon, et al.
Publicado: (2022)

Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Methoxy Poly(ethylene glycol)-b-Poly(d,l-Lactide) Polymeric Micelles Encapsulating Alpinumisoflavone Extracted from Unripe Cudrania tricuspidata Fruit
por: Jo, Min Jeong, et al.
Publicado: (2019)

Alpinumisoflavone Disrupts Endoplasmic Reticulum and Mitochondria Leading to Apoptosis in Human Ovarian Cancer
por: Hong, Taeyeon, et al.
Publicado: (2022)

Alpinumisoflavone Activates Disruption of Calcium Homeostasis, Mitochondria and Autophagosome to Suppress Development of Endometriosis
por: Song, Jisoo, et al.
Publicado: (2023)

Pegaptanib sodium for neovascular age-related macular degeneration: third-year safety results of the VEGF Inhibition Study in Ocular Neovascularisation (VISION) trial
por: Singerman, L J, et al.
Publicado: (2008)

A systematic review and meta-analysis comparing intravitreal ranibizumab with bevacizumab for the treatment of myopic choroidal neovascularisation
por: Loutfi, M., et al.
Publicado: (2015)

Combined Treatment of Photodynamic Therapy and Bevacizumab for Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
por: Kim, Hyun Woong, et al.
Publicado: (2011)

Choroidal Modifications Preceding the Onset of Macular Neovascularization in Age-Related Macular Degeneration
por: Arrigo, Alessandro, et al.
Publicado: (2021)

A randomised, double-masked phase III/IV study of the efficacy and safety of Avastin(® )(Bevacizumab) intravitreal injections compared to standard therapy in subjects with choroidal neovascularisation secondary to age-related macular degeneration: clinical trial design
por: Patel, Praveen J, et al.
Publicado: (2008)

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy
por: Sulaiman, Rania S., et al.
Publicado: (2016)

Clinical outcomes of treated macular neovascularisation secondary to inherited retinal diseases: a literature review
por: Makuloluwa, Aruni, et al.
Publicado: (2023)

Progression of subclinical choroidal neovascularization in age-related macular degeneration
por: Heiferman, Michael J., et al.
Publicado: (2019)

Choroidal Vascular Impairment in Intermediate Age-Related Macular Degeneration
por: Flores, Rita, et al.
Publicado: (2022)

Neovascularisation in tendinopathy: from eradication to stabilisation?
por: Järvinen, Tero AH
Publicado: (2020)

Hyperglycaemia Exacerbates Choroidal Neovascularisation in Mice via the Oxidative Stress-Induced Activation of STAT3 Signalling in RPE Cells
por: Li, Xia, et al.
Publicado: (2012)

A novel endothelial-derived anti-inflammatory activity significantly inhibits spontaneous choroidal neovascularisation in a mouse model
por: Paneghetti, Laura, et al.
Publicado: (2016)

Usefulness of Denoising Process to Depict Myopic Choroidal Neovascularisation Using a Single Optical Coherence Tomography Angiography Image
por: Sawai, Yuka, et al.
Publicado: (2020)

Intravitreal conbercept for choroidal neovascularisation secondary to pathological myopia in a real‐world setting in China: Intravitreal conbercept was safe and effective in treating myopic choroidal neovascularization
por: Nie, Xin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qamd1doav17704dcct8o282gtm