Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals

Integrating genetic information with metabolomics has provided new insights into genes affecting human metabolism. However, gene-metabolite integration has been primarily studied in individuals of European Ancestry, limiting the opportunity to leverage genomic diversity for discovery. In addition, t...

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Detalles Bibliográficos
Autores principales: Tahir, Usman A., Katz, Daniel H., Avila-Pachecho, Julian, Bick, Alexander G., Pampana, Akhil, Robbins, Jeremy M., Yu, Zhi, Chen, Zsu-Zsu, Benson, Mark D., Cruz, Daniel E., Ngo, Debby, Deng, Shuliang, Shi, Xu, Zheng, Shuning, Eisman, Aaron S., Farrell, Laurie, Hall, Michael E., Correa, Adolfo, Tracy, Russell P., Durda, Peter, Taylor, Kent D., Liu, Yongmei, Johnson, W. Craig, Guo, Xiuqing, Yao, Jie, Chen, Yii-Der Ida, Manichaikul, Ani W., Ruberg, Frederick L., Blaner, William S., Jain, Deepti, Bouchard, Claude, Sarzynski, Mark A., Rich, Stephen S., Rotter, Jerome I., Wang, Thomas J., Wilson, James G., Clish, Clary B., Natarajan, Pradeep, Gerszten, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395431/
https://www.ncbi.nlm.nih.gov/pubmed/35995766
http://dx.doi.org/10.1038/s41467-022-32275-3

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