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Single cell transcriptomic analysis of the immune cell compartment in the human small intestine and in Celiac disease

Celiac disease is an autoimmune disorder in which ingestion of dietary gluten triggers an immune reaction in the small intestine leading to destruction of the lining epithelium. Current treatment focusses on lifelong adherence to a gluten-free diet. Gluten-specific CD4(+) T cells and cytotoxic intra...

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Detalles Bibliográficos
Autores principales: Atlasy, Nader, Bujko, Anna, Bækkevold, Espen S., Brazda, Peter, Janssen-Megens, Eva, Lundin, Knut E. A., Jahnsen, Jørgen, Jahnsen, Frode L., Stunnenberg, Hendrik G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395525/
https://www.ncbi.nlm.nih.gov/pubmed/35995787
http://dx.doi.org/10.1038/s41467-022-32691-5