Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease

Hyperuricemia is a common biochemical disorder, which resulted from both excessive uric acid (UA) production and/or absolute or relative impairment of urinary UA excretion. Growing evidence has indicated that hyperuricemia is an independent risk factor for the development and progression of chronic...

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Autores principales: Yang, Letian, Wang, Bo, Ma, Liang, Fu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395578/
https://www.ncbi.nlm.nih.gov/pubmed/36016570
http://dx.doi.org/10.3389/fphar.2022.971032
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author Yang, Letian
Wang, Bo
Ma, Liang
Fu, Ping
author_facet Yang, Letian
Wang, Bo
Ma, Liang
Fu, Ping
author_sort Yang, Letian
collection PubMed
description Hyperuricemia is a common biochemical disorder, which resulted from both excessive uric acid (UA) production and/or absolute or relative impairment of urinary UA excretion. Growing evidence has indicated that hyperuricemia is an independent risk factor for the development and progression of chronic kidney disease (CKD), causing hyperuricemia-induced CKD (hyperuricemic nephropathy, HN). The therapeutic strategy of HN is managing hyperuricemia and protecting kidney function. Adverse effects of commercial drugs make persistent treatment of HN challenging. Traditional Chinese medicine (TCM) has exact efficacy in lowering serum UA without serious adverse effects. In addition, TCM is widely applied for the treatment of CKD. This review aimed to provide an overview of efficacy and mechanisms of traditional Chinese herbs and natural products in hyperuricemia-induced CKD.
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spelling pubmed-93955782022-08-24 Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease Yang, Letian Wang, Bo Ma, Liang Fu, Ping Front Pharmacol Pharmacology Hyperuricemia is a common biochemical disorder, which resulted from both excessive uric acid (UA) production and/or absolute or relative impairment of urinary UA excretion. Growing evidence has indicated that hyperuricemia is an independent risk factor for the development and progression of chronic kidney disease (CKD), causing hyperuricemia-induced CKD (hyperuricemic nephropathy, HN). The therapeutic strategy of HN is managing hyperuricemia and protecting kidney function. Adverse effects of commercial drugs make persistent treatment of HN challenging. Traditional Chinese medicine (TCM) has exact efficacy in lowering serum UA without serious adverse effects. In addition, TCM is widely applied for the treatment of CKD. This review aimed to provide an overview of efficacy and mechanisms of traditional Chinese herbs and natural products in hyperuricemia-induced CKD. Frontiers Media S.A. 2022-08-09 /pmc/articles/PMC9395578/ /pubmed/36016570 http://dx.doi.org/10.3389/fphar.2022.971032 Text en Copyright © 2022 Yang, Wang, Ma and Fu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Yang, Letian
Wang, Bo
Ma, Liang
Fu, Ping
Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title_full Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title_fullStr Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title_full_unstemmed Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title_short Traditional Chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
title_sort traditional chinese herbs and natural products in hyperuricemia-induced chronic kidney disease
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395578/
https://www.ncbi.nlm.nih.gov/pubmed/36016570
http://dx.doi.org/10.3389/fphar.2022.971032
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