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Induction of A Disintegrin and Metalloproteinase with Thrombospondin motifs 1 by a rare variant or cognitive activities reduces hippocampal amyloid-β and consequent Alzheimer’s disease risk

Amyloid-β (Aβ) derived from amyloid precursor protein (APP) hydrolysis is acknowledged as the predominant hallmark of Alzheimer’s disease (AD) that especially correlates to genetics and daily activities. In 2019, meta-analysis of AD has discovered five new risk loci among which A Disintegrin and Met...

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Detalles Bibliográficos
Autores principales:	Qiu, Yunjie, Sha, Longze, Zhang, Xiuneng, Li, Guanjun, Zhu, Wanwan, Xu, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395645/ https://www.ncbi.nlm.nih.gov/pubmed/36016856 http://dx.doi.org/10.3389/fnagi.2022.896522

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