Novel 3-aminobenzofuran derivatives as multifunctional agents for the treatment of Alzheimer’s disease

A novel multifunctional series of 3-aminobenzofuran derivatives 5a-p were designed and synthesized as potent inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). The target compounds 5a-p were prepared via a three-step reaction, starting from 2-hydroxy benzonitrile. In vitro...

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Detalles Bibliográficos
Autores principales: Hasanvand, Zaman, Motahari, Rasoul, Nadri, Hamid, Moghimi, Setareh, Foroumadi, Roham, Ayati, Adileh, Akbarzadeh, Tahmineh, Bukhari, Syed Nasir Abbas, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395670/
https://www.ncbi.nlm.nih.gov/pubmed/36017161
http://dx.doi.org/10.3389/fchem.2022.882191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395670/
https://www.ncbi.nlm.nih.gov/pubmed/36017161
http://dx.doi.org/10.3389/fchem.2022.882191

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