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Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations

Poly [adenosine diphosphate (ADP)-ribose] polymerases (PARPs) are members of a family of 17 enzymes that performs several fundamental cellular processes. Aberrant activity (mutation) in PARP12 has been linked to various diseases including inflammation, cardiovascular disease, and cancer. Herein, a l...

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Detalles Bibliográficos
Autores principales:	Almeleebia, Tahani M., Ahamad, Shahzaib, Ahmad, Irfan, Alshehri, Ahmad, Alkhathami, Ali G., Alshahrani, Mohammad Y., Asiri, Mohammed A., Saeed, Amir, Siddiqui, Jamshaid Ahmad, Yadav, Dharmendra K., Saeed, Mohd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9395932/ https://www.ncbi.nlm.nih.gov/pubmed/36016564 http://dx.doi.org/10.3389/fphar.2022.847499

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