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Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study
BACKGROUND: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomes in the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in two groups, who were underwent laparoscopic cystectomy and received gonadotropin releasing horm...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royan Institute
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396010/ https://www.ncbi.nlm.nih.gov/pubmed/36029058 http://dx.doi.org/10.22074/IJFS.2021.521378.1066 |
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author | Hosseinimousa, Sedigheh Safdarian, Leili Aleyasin, Ashraf Aghahosseini, Marzieh Marzieh, Talebian Talebian, Marzieh |
author_facet | Hosseinimousa, Sedigheh Safdarian, Leili Aleyasin, Ashraf Aghahosseini, Marzieh Marzieh, Talebian Talebian, Marzieh |
author_sort | Hosseinimousa, Sedigheh |
collection | PubMed |
description | BACKGROUND: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomes in the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in two groups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormone-agonist (GnRH-agonist) and who only received GnRH-agonist without any surgery. MATERIALS AND METHODS: In this prospective clinical trial study, 79 infertile women with asymptomatic endometriomas cyst (2-6 cm) were enrolled and randomly assigned to two groups. First group underwent laparoscopic cystectomy and received GnRH-agonist. Second group only received GnRH-agonist without any surgery. Following ovulation induction, all patients underwent intracytoplasmic sperm injection (ICSI). Different parameters such as the number of retrieved oocytes and embryos; were made our outcomes that analyzed using SPSS. RESULTS: The pregnancy rate, chemical and clinical, and live birth rate were higher in the combined group, although these differences were not statistically significant (48.48% vs. 30.8%, P=0.12, 36.36% vs. 25.6%, P=0.32, 36.36% vs. 23.1%, P=0.29). The number of injections, antral follicles, retrieved oocytes, mature oocytes, total embryos, transferred embryos and duration of stimulation were similar in two groups. CONCLUSION: Laparoscopic cystectomy followed by receiving GnRH-agonist improves pregnancy outcomes in endometrioma prior to treatment with ART (registration number: IRCT201106116689N2). |
format | Online Article Text |
id | pubmed-9396010 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Royan Institute |
record_format | MEDLINE/PubMed |
spelling | pubmed-93960102022-08-28 Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study Hosseinimousa, Sedigheh Safdarian, Leili Aleyasin, Ashraf Aghahosseini, Marzieh Marzieh, Talebian Talebian, Marzieh Int J Fertil Steril Original Article BACKGROUND: The purpose of this prospective study was to compare the ovarian response and pregnancy outcomes in the infertile women with endometrioma undergoing assisted reproductive technologies (ART) in two groups, who were underwent laparoscopic cystectomy and received gonadotropin releasing hormone-agonist (GnRH-agonist) and who only received GnRH-agonist without any surgery. MATERIALS AND METHODS: In this prospective clinical trial study, 79 infertile women with asymptomatic endometriomas cyst (2-6 cm) were enrolled and randomly assigned to two groups. First group underwent laparoscopic cystectomy and received GnRH-agonist. Second group only received GnRH-agonist without any surgery. Following ovulation induction, all patients underwent intracytoplasmic sperm injection (ICSI). Different parameters such as the number of retrieved oocytes and embryos; were made our outcomes that analyzed using SPSS. RESULTS: The pregnancy rate, chemical and clinical, and live birth rate were higher in the combined group, although these differences were not statistically significant (48.48% vs. 30.8%, P=0.12, 36.36% vs. 25.6%, P=0.32, 36.36% vs. 23.1%, P=0.29). The number of injections, antral follicles, retrieved oocytes, mature oocytes, total embryos, transferred embryos and duration of stimulation were similar in two groups. CONCLUSION: Laparoscopic cystectomy followed by receiving GnRH-agonist improves pregnancy outcomes in endometrioma prior to treatment with ART (registration number: IRCT201106116689N2). Royan Institute 2022 2022-08-21 /pmc/articles/PMC9396010/ /pubmed/36029058 http://dx.doi.org/10.22074/IJFS.2021.521378.1066 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited. https://creativecommons.org/licenses/by-nc/3.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial 3.0 (CC BY-NC 3.0) License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hosseinimousa, Sedigheh Safdarian, Leili Aleyasin, Ashraf Aghahosseini, Marzieh Marzieh, Talebian Talebian, Marzieh Can Laparoscopic Cystectomy Improve Pregnancy Outcomes in Endometrioma? A Prospective Clinical Trial Study |
title | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes
in Endometrioma? A Prospective Clinical Trial Study |
title_full | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes
in Endometrioma? A Prospective Clinical Trial Study |
title_fullStr | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes
in Endometrioma? A Prospective Clinical Trial Study |
title_full_unstemmed | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes
in Endometrioma? A Prospective Clinical Trial Study |
title_short | Can Laparoscopic Cystectomy Improve Pregnancy Outcomes
in Endometrioma? A Prospective Clinical Trial Study |
title_sort | can laparoscopic cystectomy improve pregnancy outcomes
in endometrioma? a prospective clinical trial study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396010/ https://www.ncbi.nlm.nih.gov/pubmed/36029058 http://dx.doi.org/10.22074/IJFS.2021.521378.1066 |
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