Binding stoichiometry and structural model of the HIV-1 Rev/importin β complex

HIV-1 Rev mediates the nuclear export of intron-containing viral RNA transcripts and is essential for viral replication. Rev is imported into the nucleus by the host protein importin β (Impβ), but how Rev associates with Impβ is poorly understood. Here, we report biochemical, mutational, and biophys...

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Detalles Bibliográficos
Autores principales: Spittler, Didier, Indorato, Rose-Laure, Boeri Erba, Elisabetta, Delaforge, Elise, Signor, Luca, Harris, Simon J, Garcia-Saez, Isabel, Palencia, Andrés, Gabel, Frank, Blackledge, Martin, Noirclerc-Savoye, Marjolaine, Petosa, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396022/
https://www.ncbi.nlm.nih.gov/pubmed/35995566
http://dx.doi.org/10.26508/lsa.202201431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396022/
https://www.ncbi.nlm.nih.gov/pubmed/35995566
http://dx.doi.org/10.26508/lsa.202201431

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