A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation

Protein phosphatase 2A (PP2A) is a major phospho-Ser/Thr phosphatase and a key regulator of cellular signal transduction pathways. While PP2A dysfunction has been linked to human cancer and neurodegenerative disorders such as Alzheimer’s disease (AD), PP2A regulation remains relatively poorly unders...

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Detalles Bibliográficos
Autores principales: Sontag, Jean-Marie, Schuhmacher, Diana, Taleski, Goce, Jordan, Anthony, Khan, Sarah, Hoffman, Alexander, Gomez, Rey J., Mazalouskas, Matthew D., Hanks, Steven K., Spiller, Benjamin W., Sontag, Estelle, Wadzinski, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396060/
https://www.ncbi.nlm.nih.gov/pubmed/35820485
http://dx.doi.org/10.1016/j.jbc.2022.102248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396060/
https://www.ncbi.nlm.nih.gov/pubmed/35820485
http://dx.doi.org/10.1016/j.jbc.2022.102248

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