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A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation
Protein phosphatase 2A (PP2A) is a major phospho-Ser/Thr phosphatase and a key regulator of cellular signal transduction pathways. While PP2A dysfunction has been linked to human cancer and neurodegenerative disorders such as Alzheimer’s disease (AD), PP2A regulation remains relatively poorly unders...
Autores principales: | Sontag, Jean-Marie, Schuhmacher, Diana, Taleski, Goce, Jordan, Anthony, Khan, Sarah, Hoffman, Alexander, Gomez, Rey J., Mazalouskas, Matthew D., Hanks, Steven K., Spiller, Benjamin W., Sontag, Estelle, Wadzinski, Brian E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396060/ https://www.ncbi.nlm.nih.gov/pubmed/35820485 http://dx.doi.org/10.1016/j.jbc.2022.102248 |
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