A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions

Active mutations in the RAS genes are found in ∼30% of human cancers. Although thought to have overlapping functions, RAS isoforms show preferential activation in human tumors, which prompted us to employ a comparative and quantitative proteomics approach to generate isoform-specific and nucleotide-...

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Detalles Bibliográficos
Autores principales: Miller, Seth P., Maio, George, Zhang, Xiaoyu, Badillo Soto, Felix S., Zhu, Julia, Ramirez, Stephen Z., Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396065/
https://www.ncbi.nlm.nih.gov/pubmed/35839996
http://dx.doi.org/10.1016/j.mcpro.2022.100268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396065/
https://www.ncbi.nlm.nih.gov/pubmed/35839996
http://dx.doi.org/10.1016/j.mcpro.2022.100268

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