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A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions
Active mutations in the RAS genes are found in ∼30% of human cancers. Although thought to have overlapping functions, RAS isoforms show preferential activation in human tumors, which prompted us to employ a comparative and quantitative proteomics approach to generate isoform-specific and nucleotide-...
Autores principales: | Miller, Seth P., Maio, George, Zhang, Xiaoyu, Badillo Soto, Felix S., Zhu, Julia, Ramirez, Stephen Z., Lin, Hening |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396065/ https://www.ncbi.nlm.nih.gov/pubmed/35839996 http://dx.doi.org/10.1016/j.mcpro.2022.100268 |
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