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hsa_circ_0115355 promotes pancreatic β‐cell function in patients with type 2 diabetes through the miR‐145/SIRT1 axis

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a complex metabolic disease closely related to obesity, a growing global health problem. T2DM is characterized by decreased islet beta‐cell mass and impaired insulin release from these cells, and this dysfunction is exacerbated by hyperglycemia (glucoli...

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Detalles Bibliográficos
Autores principales: Dai, Ying, Ma, Xudan, Zhang, Jiangnan, Yu, Shuting, Zhu, Yuchao, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396171/
https://www.ncbi.nlm.nih.gov/pubmed/35778952
http://dx.doi.org/10.1002/jcla.24583