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Rapid detection of the irinotecan‐related UGT1A1*28 polymorphism by asymmetric PCR melting curve analysis using one fluorescent probe

BACKGROUND: Determination of UGT1A1 (TA)(n) polymorphism prior to irinotecan therapy is necessary to avoid severe adverse drug effects. Thus, accurate and reliable genotyping methods for (TA)(n) polymorphism are highly desired. Here, we present a new method for polymerase chain reaction (PCR) meltin...

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Detalles Bibliográficos
Autores principales:	Kong, Xiaomu, Xu, Ye, Gao, Peng, Liu, Yi, Wang, Xuran, Zhao, Meimei, Jiang, Yongwei, Yang, Hui, Cao, Yongtong, Ma, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396174/ https://www.ncbi.nlm.nih.gov/pubmed/35766440 http://dx.doi.org/10.1002/jcla.24578

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