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Biophysical characterization of light-gated ion channels using planar automated patch clamp

Channelrhodopsins (ChRs) are proteins that guide phototaxis in protists and exhibit light-gated channel conductance when their genes are heterologously expressed in mammalian cells. ChRs are widely used as molecular tools to control neurons and cardiomyocytes with light (optogenetics). Cation- and a...

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Detalles Bibliográficos
Autores principales: Govorunova, Elena G., Sineshchekov, Oleg A., Brown, Leonid S., Spudich, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396214/
https://www.ncbi.nlm.nih.gov/pubmed/36017077
http://dx.doi.org/10.3389/fnmol.2022.976910

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