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Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review

Despite the rare incidence of idiopathic pulmonary fibrosis (IPF), coexisting IPF and lung cancer is common. Both diseases have unfavorable outcomes and are often associated with impaired quality of life. In this study, we present a clinical case of a patient with coexisting IPF and lung adenocarcin...

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Autores principales: Zlatanova, Tanya, Arabadjiev, Jeliazko, Kirova-Nedyalkova, Galina, Nikova, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396293/
https://www.ncbi.nlm.nih.gov/pubmed/36016602
http://dx.doi.org/10.3389/fonc.2022.907321
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author Zlatanova, Tanya
Arabadjiev, Jeliazko
Kirova-Nedyalkova, Galina
Nikova, Diana
author_facet Zlatanova, Tanya
Arabadjiev, Jeliazko
Kirova-Nedyalkova, Galina
Nikova, Diana
author_sort Zlatanova, Tanya
collection PubMed
description Despite the rare incidence of idiopathic pulmonary fibrosis (IPF), coexisting IPF and lung cancer is common. Both diseases have unfavorable outcomes and are often associated with impaired quality of life. In this study, we present a clinical case of a patient with coexisting IPF and lung adenocarcinoma who was successfully treated with nintedanib plus docetaxel as a second-line treatment, and achieved a substantial improvement in the quality of life. To our knowledge, very few cases in the literature address the concurrent treatment of both diseases, which makes this case a valuable illustration of a successful treatment strategy and a basis for future investigations.
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spelling pubmed-93962932022-08-24 Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review Zlatanova, Tanya Arabadjiev, Jeliazko Kirova-Nedyalkova, Galina Nikova, Diana Front Oncol Oncology Despite the rare incidence of idiopathic pulmonary fibrosis (IPF), coexisting IPF and lung cancer is common. Both diseases have unfavorable outcomes and are often associated with impaired quality of life. In this study, we present a clinical case of a patient with coexisting IPF and lung adenocarcinoma who was successfully treated with nintedanib plus docetaxel as a second-line treatment, and achieved a substantial improvement in the quality of life. To our knowledge, very few cases in the literature address the concurrent treatment of both diseases, which makes this case a valuable illustration of a successful treatment strategy and a basis for future investigations. Frontiers Media S.A. 2022-08-09 /pmc/articles/PMC9396293/ /pubmed/36016602 http://dx.doi.org/10.3389/fonc.2022.907321 Text en Copyright © 2022 Zlatanova, Arabadjiev, Kirova-Nedyalkova and Nikova https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zlatanova, Tanya
Arabadjiev, Jeliazko
Kirova-Nedyalkova, Galina
Nikova, Diana
Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title_full Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title_fullStr Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title_full_unstemmed Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title_short Successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: A case report and literature review
title_sort successful treatment with docetaxel plus nintedanib in a patient with lung adenocarcinoma and pulmonary fibrosis: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396293/
https://www.ncbi.nlm.nih.gov/pubmed/36016602
http://dx.doi.org/10.3389/fonc.2022.907321
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