Erythropoietin mediates re-programming of endotoxin-tolerant macrophages through PI3K/AKT signaling and protects mice against secondary infection

Initial lipopolysaccharide (LPS) exposure leads to a hypo-responsive state by macrophages to a secondary stimulation of LPS, known as endotoxin tolerance. However, recent findings show that functions of endotoxin-tolerant macrophages are not completely suppressed, whereas they undergo a functional r...

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Detalles Bibliográficos
Autores principales: Zhang, Xue, He, Dan, Jia, Jialin, Liang, Feihong, Mei, Jie, Li, Wenhua, Liu, Tingting, Wang, Zhiyu, Liu, Yu, Zhang, Fengxue, Zhang, Zhiren, Luo, Bangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396350/
https://www.ncbi.nlm.nih.gov/pubmed/36016936
http://dx.doi.org/10.3389/fimmu.2022.938944

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