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Methodological advances and strategies for high resolution structure determination of cellular protein aggregates

Aggregation of proteins is at the nexus of molecular processes crucial to aging, disease, and employing proteins for biotechnology and medical applications. There has been much recent progress in determining the structural features of protein aggregates that form in cells; yet, owing to prevalent he...

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Detalles Bibliográficos
Autores principales: Schaefer, Anna, Naser, Dalia, Siebeneichler, Bruna, Tarasca, Michael V., Meiering, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396402/
https://www.ncbi.nlm.nih.gov/pubmed/35760099
http://dx.doi.org/10.1016/j.jbc.2022.102197