Single amino acids set apparent temperature thresholds for heat-evoked activation of mosquito transient receptor potential channel TRPA1

Animals detect heat using thermosensitive transient receptor potential (TRP) channels. In insects, these include TRP ankyrin 1 (TRPA1), which in mosquitoes is crucial for noxious heat avoidance and thus is an appealing pest control target. However, the molecular basis for heat-evoked activation has...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Hong Dung, Chapman, Stella, Kashio, Makiko, Saito, Claire, Strom, Tatjana, Yasui, Mio, Tominaga, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396403/
https://www.ncbi.nlm.nih.gov/pubmed/35850302
http://dx.doi.org/10.1016/j.jbc.2022.102271

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