Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium

In the mammalian retina, a metabolic ecosystem exists in which photoreceptors acquire glucose from the choriocapillaris with the help of the retinal pigment epithelium (RPE). While the photoreceptor cells are primarily glycolytic, exhibiting Warburg-like metabolism, the RPE is reliant on mitochondri...

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Detalles Bibliográficos
Autores principales: Hazim, Roni A., Paniagua, Antonio E., Tang, Lisa, Yang, Krista, Kim, Kristen K.O., Stiles, Linsey, Divakaruni, Ajit S., Williams, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396405/
https://www.ncbi.nlm.nih.gov/pubmed/35868562
http://dx.doi.org/10.1016/j.jbc.2022.102286

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