EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex

Insulin signaling in blood vessels primarily functions to stimulate angiogenesis and maintain vascular homeostasis through the canonical PI3K and MAPK signaling pathways. However, angiogenesis is a complex process coordinated by multiple other signaling events. Here, we report a distinct crosstalk b...

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Detalles Bibliográficos
Autores principales: Ahmed, Tasmia, Flores, Paola Cruz, Pan, Christopher C., Ortiz, Hannah R., Lee, Yeon S., Langlais, Paul R., Mythreye, Karthikeyan, Lee, Nam Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396412/
https://www.ncbi.nlm.nih.gov/pubmed/35872017
http://dx.doi.org/10.1016/j.jbc.2022.102297

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