Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to a successive stimulus

Immediate early genes (IEGs) are transcribed in response to neuronal activity from sensory stimulation during multiple adaptive processes in the brain. The transcriptional profile of IEGs is indicative of the duration of neuronal activity, but its sensitivity to the strength of depolarization remain...

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Detalles Bibliográficos
Autores principales: Rienecker, Kira D.A., Poston, Robert G., Segales, Joshua S., Finholm, Isabelle W., Sono, Morgan H., Munteanu, Sorina J., Ghaninejad-Esfahani, Mina, Rejepova, Ayna, Tejeda-Garibay, Susana, Wickman, Kevin, Marron Fernandez de Velasco, Ezequiel, Thayer, Stanley A., Saha, Ramendra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396413/
https://www.ncbi.nlm.nih.gov/pubmed/35863435
http://dx.doi.org/10.1016/j.jbc.2022.102278

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