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An antagonistic monoclonal anti–Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis

Osteoporosis and multiple sclerosis are highly prevalent diseases with limited treatment options. In light of these unmet medical needs, novel therapeutic approaches are urgently sought. Previously, the activation of the transmembrane receptor Plexin-B1 by its ligand semaphorin 4D (Sema4D) has been...

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Detalles Bibliográficos
Autores principales:	Vogler, Melanie, Oleksy, Arkadiusz, Schulze, Sabrina, Fedorova, Marina, Kojonazarov, Baktybek, Nijjar, Sharandip, Patel, Seema, Jossi, Sian, Sawmynaden, Kovilen, Henry, Maud, Brown, Richard, Matthews, David, Offermanns, Stefan, Worzfeld, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396414/ https://www.ncbi.nlm.nih.gov/pubmed/35850304 http://dx.doi.org/10.1016/j.jbc.2022.102265

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