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Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia

COVID-19 is a global health crisis that has impacted the world with heavy economic and social losses. In the early days of the pandemic, pediatric COVID-19 was well-known for its low infectivity and mortality rates as well as its benign clinical outcomes. Herein, we report the case of a 6-year-old g...

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Autores principales: Asseri, Ali Alsuheel, Assiri, Mohammed, Alshehri, Mohammed Abdullah, Asseri, Malak, Ali, Abdelwahid Saeed, Awadalla, Nabil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396438/
https://www.ncbi.nlm.nih.gov/pubmed/35998873
http://dx.doi.org/10.1016/j.ijid.2022.08.013
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author Asseri, Ali Alsuheel
Assiri, Mohammed
Alshehri, Mohammed Abdullah
Asseri, Malak
Ali, Abdelwahid Saeed
Awadalla, Nabil J.
author_facet Asseri, Ali Alsuheel
Assiri, Mohammed
Alshehri, Mohammed Abdullah
Asseri, Malak
Ali, Abdelwahid Saeed
Awadalla, Nabil J.
author_sort Asseri, Ali Alsuheel
collection PubMed
description COVID-19 is a global health crisis that has impacted the world with heavy economic and social losses. In the early days of the pandemic, pediatric COVID-19 was well-known for its low infectivity and mortality rates as well as its benign clinical outcomes. Herein, we report the case of a 6-year-old girl with COVID-19-associated encephalopathy without respiratory symptoms. To the best of our knowledge, this is the first child reported from Saudi Arabia with COVID-19-induced encephalopathy. A 6-year-old patient with COVID-19 was presented to the Abha Maternity and Child Hospital in southeastern Saudi Arabia. Routine clinical and laboratory examinations revealed normal findings. Despite the absence of COVID-19 respiratory manifestations, the patient manifested COVID-19-related encephalopathy. The patient responded well to pulse steroid, favipiravir, and symptomatic seizure therapies. The patient recovered completely without any neurologic morbidities. A COVID-19-related encephalopathy was observed for the first time in Saudi Arabia among pediatric patients. Clinicians should be alert to potential neurologic complications associated with COVID-19. It should be considered in the differential diagnosis of children presenting with acute encephalopathy, even in the absence of respiratory symptoms. To avoid long-term neurologic sequelae, prompt seizure and immunosuppressive therapies are essential.
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spelling pubmed-93964382022-08-23 Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia Asseri, Ali Alsuheel Assiri, Mohammed Alshehri, Mohammed Abdullah Asseri, Malak Ali, Abdelwahid Saeed Awadalla, Nabil J. Int J Infect Dis Case Report COVID-19 is a global health crisis that has impacted the world with heavy economic and social losses. In the early days of the pandemic, pediatric COVID-19 was well-known for its low infectivity and mortality rates as well as its benign clinical outcomes. Herein, we report the case of a 6-year-old girl with COVID-19-associated encephalopathy without respiratory symptoms. To the best of our knowledge, this is the first child reported from Saudi Arabia with COVID-19-induced encephalopathy. A 6-year-old patient with COVID-19 was presented to the Abha Maternity and Child Hospital in southeastern Saudi Arabia. Routine clinical and laboratory examinations revealed normal findings. Despite the absence of COVID-19 respiratory manifestations, the patient manifested COVID-19-related encephalopathy. The patient responded well to pulse steroid, favipiravir, and symptomatic seizure therapies. The patient recovered completely without any neurologic morbidities. A COVID-19-related encephalopathy was observed for the first time in Saudi Arabia among pediatric patients. Clinicians should be alert to potential neurologic complications associated with COVID-19. It should be considered in the differential diagnosis of children presenting with acute encephalopathy, even in the absence of respiratory symptoms. To avoid long-term neurologic sequelae, prompt seizure and immunosuppressive therapies are essential. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022-10 2022-08-23 /pmc/articles/PMC9396438/ /pubmed/35998873 http://dx.doi.org/10.1016/j.ijid.2022.08.013 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Asseri, Ali Alsuheel
Assiri, Mohammed
Alshehri, Mohammed Abdullah
Asseri, Malak
Ali, Abdelwahid Saeed
Awadalla, Nabil J.
Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title_full Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title_fullStr Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title_full_unstemmed Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title_short Acute encephalopathy in a 6-year-old child with concurrent COVID-19 infection: a case report from Saudi Arabia
title_sort acute encephalopathy in a 6-year-old child with concurrent covid-19 infection: a case report from saudi arabia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396438/
https://www.ncbi.nlm.nih.gov/pubmed/35998873
http://dx.doi.org/10.1016/j.ijid.2022.08.013
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