A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection

Immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ) in PfSPZ Vaccine, has provided better vaccine efficacy (VE) against controlled human malaria infection (CHMI) with the same parasites as in the vaccine (homologous) than with genetically distant parasites (heterologo...

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Detalles Bibliográficos
Autores principales: Mordmüller, Benjamin, Sulyok, Zita, Sulyok, Mihály, Molnar, Zsofia, Lalremruata, Albert, Calle, Carlos Lamsfus, Bayon, Patricia Granados, Esen, Meral, Gmeiner, Markus, Held, Jana, Heimann, Henri-Lynn, Woldearegai, Tamirat Gebru, Ibáñez, Javier, Flügge, Judith, Fendel, Rolf, Kreidenweiss, Andrea, KC, Natasha, Murshedkar, Tooba, Chakravarty, Sumana, Riyahi, Pouria, Billingsley, Peter F., Church, L. W. Preston, Richie, Thomas L., Sim, B. Kim Lee, Hoffman, Stephen L., Kremsner, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396563/
https://www.ncbi.nlm.nih.gov/pubmed/35999221
http://dx.doi.org/10.1038/s41541-022-00510-z

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