Cargando…

Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons

BACKGROUND: Biological aging represents a loss of integrity and functionality of physiological systems over time. While associated with an enhanced risk of adverse outcomes such as hospitalization, disability and death following infection, its role in perceived age-related declines in vaccine respon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verschoor, Chris P., Belsky, Daniel W., Andrew, Melissa K., Haynes, Laura, Loeb, Mark, Pawelec, Graham, McElhaney, Janet E., Kuchel, George A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396565/ https://www.ncbi.nlm.nih.gov/pubmed/35999604 http://dx.doi.org/10.1186/s12979-022-00296-7

Ejemplares similares

Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults
por: Verschoor, Chris P., et al.
Publicado: (2021)

Corrigendum: Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults
por: Verschoor, Chris P., et al.
Publicado: (2021)

Granzyme B: A Double-Edged Sword in the Response to Influenza Infection in Vaccinated Older Adults
por: Verschoor, Chris P., et al.
Publicado: (2021)

Antibody and Cell-Mediated Immune Responses Are Correlates of Protection against Influenza Infection in Vaccinated Older Adults
por: Verschoor, Chris P., et al.
Publicado: (2021)

The immune response to influenza in older humans: beyond immune senescence
por: McElhaney, Janet E., et al.
Publicado: (2020)

Improving seasonal influenza vaccination for older adults
por: Pawelec, Graham, et al.
Publicado: (2021)

Markers of systemic inflammation are positively associated with influenza vaccine antibody responses with a possible role for ILT2(+)CD57(+) NK-cells
por: Picard, Emilie, et al.
Publicado: (2022)

Frailty Is Associated With Increased Hemagglutination-Inhibition Titers in a 4-Year Randomized Trial Comparing Standard- and High-Dose Influenza Vaccination
por: Loeb, Nathalie, et al.
Publicado: (2020)

Impact of Aging and Cytomegalovirus on Immunological Response to Influenza Vaccination and Infection
por: Merani, Shahzma, et al.
Publicado: (2017)

Recent advances in influenza vaccines
por: Pawelec, Graham, et al.
Publicado: (2020)

Vaccines for Improved Cellular Immunity to Influenza
por: Pawelec, Graham, et al.
Publicado: (2018)

NK- and T-cell granzyme B and K expression correlates with age, CMV infection and influenza vaccine-induced antibody titres in older adults
por: Verschoor, Chris P., et al.
Publicado: (2023)

Unanticipated efficacy of SARS-CoV-2 vaccination in older adults
por: Pawelec, Graham, et al.
Publicado: (2021)

Reliable reference genes for the quantification of mRNA in human T-cells and PBMCs stimulated with live influenza virus
por: Roy, Justin G., et al.
Publicado: (2020)

T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines
por: McElhaney, Janet E., et al.
Publicado: (2016)

Impact of Prior Season Influenza Vaccination on Seasonal Influenza Vaccine Effectiveness: An Analysis over Four Consecutive Seasons from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)
por: Nichols, Michaela, et al.
Publicado: (2017)

IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans
por: Zhou, Xin, et al.
Publicado: (2016)

Immunosenescence and Influenza Vaccine Efficacy
por: Sambhara, Suryaprakash, et al.
Publicado: (2009)

Cytomegalovirus Seropositivity Predicts a Decline in the T Cell But Not the Antibody Response to Influenza in Vaccinated Older Adults Independent of Type 2 Diabetes Status
por: Haq, Kamran, et al.
Publicado: (2017)

Predictors of the antibody response to influenza vaccination in older adults with type 2 diabetes
por: McElhaney, Janet E, et al.
Publicado: (2015)

Age and frailty in COVID-19 vaccine development
por: Andrew, Melissa K, et al.
Publicado: (2021)

Immunosenescence Modulation by Vaccination
por: McElhaney, Janet E.
Publicado: (2008)

Immunosenescence Modulation by Vaccination
por: McElhaney, Janet E.
Publicado: (2019)

Influence of Obesity on Pneumococcus Infection Risk in the Elderly
por: Frasca, Daniela, et al.
Publicado: (2019)

Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada
por: Andrew, Melissa K., et al.
Publicado: (2017)

Epidemiology of Influenza Viruses in Canada over the 2011–2012 to 2013–2014 Seasons: A Study from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN)
por: Elsherif, May, et al.
Publicado: (2017)

Relative Vaccine Effectiveness of Adjuvanted Trivalent Influenza Vaccine over Three Consecutive Influenza Seasons in the United States
por: Boikos, Constantina, et al.
Publicado: (2022)

ENDOCRINES AND THEIR RELATION TO INFLUENZA VIRUS INFECTION
por: Kalter, Seymour S., et al.
Publicado: (1951)

Epidemiology and Burden of Influenza in Children 0–14 Years Over Ten Consecutive Seasons in Italy
por: Barbieri, Elisa, et al.
Publicado: (2023)

Epidemiology and seasonality of acute respiratory infections in hospitalized children over four consecutive years (2012–2016)
por: Fillatre, Adrien, et al.
Publicado: (2018)

Influenza vaccination of pregnant women protects them over two consecutive influenza seasons in a randomized controlled trial
por: Mutsaerts, Eleonora, et al.
Publicado: (2016)

Influenza-Specific T Cells from Older People Are Enriched in the Late Effector Subset and Their Presence Inversely Correlates with Vaccine Response
por: Wagar, Lisa E., et al.
Publicado: (2011)

Influenza vaccination coverage rates in five European countries during season 2006/07 and trends over six consecutive seasons
por: Blank, Patricia R, et al.
Publicado: (2008)

Influenza Vaccine Effectiveness Estimates among US Department of Defense Adult Beneficiaries over Four Consecutive Influenza Seasons: A Test-Negative Design Study with Different Control Groups
por: Hu, Wenping, et al.
Publicado: (2021)

Efficacy and Safety of CVT-E002, a Proprietary Extract of Panax quinquefolius in the Prevention of Respiratory Infections in Influenza-Vaccinated Community-Dwelling Adults: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Trial
por: McElhaney, Janet E., et al.
Publicado: (2011)

Successional Trajectories of Rhizosphere Bacterial Communities over Consecutive Seasons
por: Shi, Shengjing, et al.
Publicado: (2015)

Molecular influenza surveillance at a tertiary university hospital during four consecutive seasons (2012–2016) in Catalonia, Spain
por: Andrés, Cristina, et al.
Publicado: (2019)

Key policy and programmatic factors to improve influenza vaccination rates based on the experience from four high-performing countries
por: Kassianos, George, et al.
Publicado: (2021)

A Contributing Role for Anti-Neuraminidase Antibodies on Immunity to Pandemic H1N1 2009 Influenza A Virus
por: Marcelin, Glendie, et al.
Publicado: (2011)

992. 2016–2017 Influenza Burden of Disease and End-of-Season Influenza Vaccine Effectiveness (VE) Estimates for Preventing Influenza-Related Hospitalization Among Canadian Adults: An Analysis From the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network
por: Nichols, Michaela, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7tnl8s3as5cjrufrc44ff4e45i