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Cleavage Off-Loading and Post-assembly-Line Conversions Yield Products with Unusual Termini during Biosynthesis

[Image: see text] Piscibactins and photoxenobactins are metallophores and virulence factors, whose biosynthetic gene cluster, termed pxb, is the most prevalent polyketide synthase/non-ribosomal peptide synthetase hybrid cluster across entomopathogenic bacteria. They are structurally similar to yersi...

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Detalles Bibliográficos
Autores principales: Shi, Yi-Ming, Hirschmann, Merle, Shi, Yan-Ni, Bode, Helge B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396620/
https://www.ncbi.nlm.nih.gov/pubmed/35860925
http://dx.doi.org/10.1021/acschembio.2c00367