Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

OBJECTIVES: Tirzepatide, a dual GIP and GLP-1 receptor agonist, delivered superior glycemic control and weight loss compared to selective GLP-1 receptor (GLP-1R) agonism in patients with type 2 diabetes (T2D). These results have fueled mechanistic studies focused on understanding how tirzepatide ach...

Descripción completa

Detalles Bibliográficos
Autores principales: Samms, Ricardo J., Zhang, GuoFang, He, Wentao, Ilkayeva, Olga, Droz, Brian A., Bauer, Steven M., Stutsman, Cynthia, Pirro, Valentina, Collins, Kyla A., Furber, Ellen C., Coskun, Tamer, Sloop, Kyle W., Brozinick, Joseph T., Newgard, Christopher B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396640/
https://www.ncbi.nlm.nih.gov/pubmed/35921984
http://dx.doi.org/10.1016/j.molmet.2022.101550

Ejemplares similares

Ejemplares similares