Cargando…

Effect of AKT silence on malignant biological behavior of renal cell carcinoma cells

BACKGROUND: As the most common malignant tumor of primary renal tumor, renal cell carcinoma (RCC) is the highly invasive disease with high mortality. AKT is a serine/threonine kinase that play a critical role in the phosphoinositide 3-kinase (PI3K) signaling pathway, and it is an attractive target f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zuan, Nong, DeYong, Li, Bincai, Wang, Haojian, Li, Chunlin, Chen, Zhi, Li, Ximing, Huang, Guihai, Lin, Junhao, Hao, Nan, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396790/ https://www.ncbi.nlm.nih.gov/pubmed/35996134 http://dx.doi.org/10.1186/s12894-022-01087-4

Ejemplares similares

Speckle-type POZ protein could play a potential inhibitory role in human renal cell carcinoma
por: Chen, Zhi, et al.
Publicado: (2022)

High expression of TTC21A predicts unfavorable prognosis and immune infiltrates in clear cell renal cell carcinoma
por: Lin, Junhao, et al.
Publicado: (2022)

Screening of hub genes and evaluation of the growth regulatory role of CD44 in metastatic prostate cancer
por: Lin, Junhao, et al.
Publicado: (2021)

Screening of hub genes and evaluation of the growth regulatory role of CD44 in metastatic prostate cancer
por: Lin, Junhao, et al.
Publicado: (2022)

The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue
por: Li, Ximing, et al.
Publicado: (2020)

Effect of CEACAM6 silencing on the biological behavior of human gallbladder cancer cells
por: Tian, Chengming, et al.
Publicado: (2020)

Concise Review: Exploiting Unique Biological Features of Leukemia Stem Cells for Therapeutic Benefit
por: Zhang, Haojian, et al.
Publicado: (2019)

Editorial: Characteristics and behaviors of hematopoietic stem cells and leukemia stem cells in hematologic malignancies
por: Zhang, Haojian, et al.
Publicado: (2022)

Effect of cycloxygenase-2 silencing on the malignant biological behavior of MCF-7 breast cancer cells
por: YANG, SHENG, et al.
Publicado: (2014)

circRNA THBS1 silencing inhibits the malignant biological behavior of cervical cancer cells via the regulation of miR-543/HMGB2 axis
por: Tian, Rui, et al.
Publicado: (2023)

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells
por: Lin, Weiguo, et al.
Publicado: (2020)

HMGN5 Silencing Suppresses Cell Biological Progression via AKT/MAPK Pathway in Human Glioblastoma Cells
por: Ma, Quanfeng, et al.
Publicado: (2020)

Heat Shock Protein 90 and Role of Its Chemical Inhibitors in Treatment of Hematologic Malignancies
por: Ho, Ngoc, et al.
Publicado: (2012)

CD44 regulates prostate cancer proliferation, invasion and migration via PDK1 and PFKFB4
por: Li, Wei, et al.
Publicado: (2017)

Silencing novel long non-coding RNA FKBP9P1 represses malignant progression and inhibits PI3K/AKT signaling of head and neck squamous cell carcinoma in vitro
por: Yang, Yi-Fan, et al.
Publicado: (2020)

Silencing of LncRNA C1RL-AS1 Suppresses the Malignant Phenotype in Gastric Cancer Cells via the AKT/β-Catenin/c-Myc Pathway
por: Zhen-Hua, Wu, et al.
Publicado: (2020)

Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF‐κB signaling
por: Xu, Hongying, et al.
Publicado: (2017)

Gene silencing of galectin-3 changes the biological behavior of Eca109 human esophageal cancer cells
por: QIAO, LILI, et al.
Publicado: (2016)

CIP2A interacts with AKT1 to promote the malignant biological behaviors of oral squamous cell carcinoma by upregulating the GSK‑3β/β‑catenin pathway
por: Che, Yilei, et al.
Publicado: (2023)

Silencing LINC01116 suppresses the development of lung adenocarcinoma via the AKT signaling pathway
por: Shang, Bin, et al.
Publicado: (2021)

Development and validation of a PBRM1‐associated immune prognostic model for clear cell renal cell carcinoma
por: Chen, Jiayi, et al.
Publicado: (2021)

Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma
por: Yang, Chen, et al.
Publicado: (2022)

Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells
por: Zhang, Yi, et al.
Publicado: (2011)

PESV represses non-small cell lung cancer cell malignancy through circ_0016760 under hypoxia
por: Zhang, Hong, et al.
Publicado: (2021)

ARNTL inhibits the malignant behaviors of oral cancer by regulating autophagy in an AKT/mTOR pathway‐dependent manner
por: Chen, KuiChi, et al.
Publicado: (2023)

Inhibiting cell migration and cell invasion by silencing the transcription factor ETS-1 in human bladder cancer
por: Liu, Li, et al.
Publicado: (2016)

GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT
por: Xu, En, et al.
Publicado: (2020)

Effect of silencing C-erbB-2 on esophageal carcinoma cell biological behaviors by inhibiting IGF-1 pathway activation
por: Niu, Zhigao, et al.
Publicado: (2021)

Silencing of Synuclein-γ inhibits human cervical cancer through the AKT signaling pathway
por: Zhang, Chunnian, et al.
Publicado: (2019)

Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway
por: Li, Pu, et al.
Publicado: (2017)

Silencing SATB1 Inhibits the Malignant Phenotype and Increases Sensitivity of Human Osteosarcoma U2OS Cells to Arsenic Trioxide
por: Zhang, Haiying, et al.
Publicado: (2014)

Silencing of STRN4 suppresses the malignant characteristics of cancer cells
por: Wong, Meihong, et al.
Publicado: (2014)

Methylation-Mediated Silencing of RBP7 Promotes Breast Cancer Progression through PPAR and PI3K/AKT Pathway
por: Lin, Hong, et al.
Publicado: (2022)

Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression
por: Gong, Xuelian, et al.
Publicado: (2021)

Elevation of MAP17 enhances the malignant behavior of cells via the Akt/mTOR pathway in hepatocellular carcinoma
por: Chen, Xinhuang, et al.
Publicado: (2017)

Correction: Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma
por: Yang, Chen, et al.
Publicado: (2022)

De novo induction of lineage plasticity from human prostate luminal epithelial cells by activated AKT1 and c-Myc
por: Kwon, Oh-Joon, et al.
Publicado: (2020)

Silencing Of MAGI1 Promotes The Proliferation And Inhibits Apoptosis Of Glioma Cells Via The Wnt/β-Catenin And PTEN/AKT Signaling Pathways
por: Lu, Yongzhi, et al.
Publicado: (2019)

Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathway
por: Cao, Zhengyong, et al.
Publicado: (2021)

Silencing circular RNA circ_0054537 and upregulating microRNA-640 suppress malignant progression of renal cell carcinoma via regulating neuronal pentraxin-2 (NPTX2)
por: Pei, Long, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ekttg78ckq2a1jf2fm161qglg6