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Strain specific properties of Escherichia coli can prevent non-canonical amino acid misincorporation caused by scale-related process heterogeneities

BACKGROUND: Escherichia coli is one of the most important hosts for production of recombinant proteins in biopharmaceutical industry. However, when selecting a suitable production strain, it is often not considered that a lot of different sub-species exist, which can differ in their genotypes and ph...

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Detalles Bibliográficos
Autores principales:	Mayer, Florian, Cserjan-Puschmann, Monika, Haslinger, Benedikt, Shpylovyi, Anton, Dalik, Thomas, Sam, Christian, Hahn, Rainer, Striedner, Gerald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396823/ https://www.ncbi.nlm.nih.gov/pubmed/35999607 http://dx.doi.org/10.1186/s12934-022-01895-1

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