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BDNF-dependent modulation of axonal transport is selectively impaired in ALS

Axonal transport ensures long-range delivery of essential cargoes between proximal and distal compartments, and is needed for neuronal development, function, and survival. Deficits in axonal transport have been detected at pre-symptomatic stages in the SOD1(G93A) and TDP-43(M337V) mouse models of am...

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Detalles Bibliográficos
Autores principales:	Tosolini, Andrew P., Sleigh, James N., Surana, Sunaina, Rhymes, Elena R., Cahalan, Stephen D., Schiavo, Giampietro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396851/ https://www.ncbi.nlm.nih.gov/pubmed/35996201 http://dx.doi.org/10.1186/s40478-022-01418-4

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