Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy

BACKGROUND: The PD-1 checkpoint pathway plays a major role in tumor immune evasion and the development of the tumor microenvironment. Clinical studies show that therapeutic antibodies blocking the PD-1 pathway can restore anti-tumor or anti-virus immune responses by the reinvigoration of exhausted T...

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Detalles Bibliográficos
Autores principales: Ghaderi, Sepideh Safaei, Riazi-Rad, Farhad, Qamsari, Elmira Safaie, Bagheri, Salman, Rahimi-Jamnani, Fatemeh, Sharifzadeh, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396865/
https://www.ncbi.nlm.nih.gov/pubmed/35996120
http://dx.doi.org/10.1186/s12896-022-00752-8

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