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ESBL plasmids in Klebsiella pneumoniae: diversity, transmission and contribution to infection burden in the hospital setting

BACKGROUND: Resistance to third-generation cephalosporins, often mediated by extended-spectrum beta-lactamases (ESBLs), is a considerable issue in hospital-associated infections as few drugs remain for treatment. ESBL genes are often located on large plasmids that transfer horizontally between strai...

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Detalles Bibliográficos
Autores principales: Hawkey, Jane, Wyres, Kelly L., Judd, Louise M., Harshegyi, Taylor, Blakeway, Luke, Wick, Ryan R., Jenney, Adam W. J., Holt, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396894/
https://www.ncbi.nlm.nih.gov/pubmed/35999578
http://dx.doi.org/10.1186/s13073-022-01103-0

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