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ESBL plasmids in Klebsiella pneumoniae: diversity, transmission and contribution to infection burden in the hospital setting
BACKGROUND: Resistance to third-generation cephalosporins, often mediated by extended-spectrum beta-lactamases (ESBLs), is a considerable issue in hospital-associated infections as few drugs remain for treatment. ESBL genes are often located on large plasmids that transfer horizontally between strai...
Autores principales: | Hawkey, Jane, Wyres, Kelly L., Judd, Louise M., Harshegyi, Taylor, Blakeway, Luke, Wick, Ryan R., Jenney, Adam W. J., Holt, Kathryn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396894/ https://www.ncbi.nlm.nih.gov/pubmed/35999578 http://dx.doi.org/10.1186/s13073-022-01103-0 |
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