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Alginate-Based Bio-Composites and Their Potential Applications

Over the last two decades, bio-polymer fibers have attracted attention for their uses in gene therapy, tissue engineering, wound-healing, and controlled drug delivery. The most commonly used bio-polymers are bio-sourced synthetic polymers such as poly (glycolic acid), poly (lactic acid), poly (e-cap...

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Autores principales: Zdiri, Khmais, Cayla, Aurélie, Elamri, Adel, Erard, Annaëlle, Salaun, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397003/
https://www.ncbi.nlm.nih.gov/pubmed/35997455
http://dx.doi.org/10.3390/jfb13030117
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author Zdiri, Khmais
Cayla, Aurélie
Elamri, Adel
Erard, Annaëlle
Salaun, Fabien
author_facet Zdiri, Khmais
Cayla, Aurélie
Elamri, Adel
Erard, Annaëlle
Salaun, Fabien
author_sort Zdiri, Khmais
collection PubMed
description Over the last two decades, bio-polymer fibers have attracted attention for their uses in gene therapy, tissue engineering, wound-healing, and controlled drug delivery. The most commonly used bio-polymers are bio-sourced synthetic polymers such as poly (glycolic acid), poly (lactic acid), poly (e-caprolactone), copolymers of polyglycolide and poly (3-hydroxybutyrate), and natural polymers such as chitosan, soy protein, and alginate. Among all of the bio-polymer fibers, alginate is endowed with its ease of sol–gel transformation, remarkable ion exchange properties, and acid stability. Blending alginate fibers with a wide range of other materials has certainly opened many new opportunities for applications. This paper presents an overview on the modification of alginate fibers with nano-particles, adhesive peptides, and natural or synthetic polymers, in order to enhance their properties. The application of alginate fibers in several areas such as cosmetics, sensors, drug delivery, tissue engineering, and water treatment are investigated. The first section is a brief theoretical background regarding the definition, the source, and the structure of alginate. The second part deals with the physico-chemical, structural, and biological properties of alginate bio-polymers. The third part presents the spinning techniques and the effects of the process and solution parameters on the thermo-mechanical and physico-chemical properties of alginate fibers. Then, the fourth part presents the additives used as fillers in order to improve the properties of alginate fibers. Finally, the last section covers the practical applications of alginate composite fibers.
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spelling pubmed-93970032022-08-24 Alginate-Based Bio-Composites and Their Potential Applications Zdiri, Khmais Cayla, Aurélie Elamri, Adel Erard, Annaëlle Salaun, Fabien J Funct Biomater Review Over the last two decades, bio-polymer fibers have attracted attention for their uses in gene therapy, tissue engineering, wound-healing, and controlled drug delivery. The most commonly used bio-polymers are bio-sourced synthetic polymers such as poly (glycolic acid), poly (lactic acid), poly (e-caprolactone), copolymers of polyglycolide and poly (3-hydroxybutyrate), and natural polymers such as chitosan, soy protein, and alginate. Among all of the bio-polymer fibers, alginate is endowed with its ease of sol–gel transformation, remarkable ion exchange properties, and acid stability. Blending alginate fibers with a wide range of other materials has certainly opened many new opportunities for applications. This paper presents an overview on the modification of alginate fibers with nano-particles, adhesive peptides, and natural or synthetic polymers, in order to enhance their properties. The application of alginate fibers in several areas such as cosmetics, sensors, drug delivery, tissue engineering, and water treatment are investigated. The first section is a brief theoretical background regarding the definition, the source, and the structure of alginate. The second part deals with the physico-chemical, structural, and biological properties of alginate bio-polymers. The third part presents the spinning techniques and the effects of the process and solution parameters on the thermo-mechanical and physico-chemical properties of alginate fibers. Then, the fourth part presents the additives used as fillers in order to improve the properties of alginate fibers. Finally, the last section covers the practical applications of alginate composite fibers. MDPI 2022-08-10 /pmc/articles/PMC9397003/ /pubmed/35997455 http://dx.doi.org/10.3390/jfb13030117 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zdiri, Khmais
Cayla, Aurélie
Elamri, Adel
Erard, Annaëlle
Salaun, Fabien
Alginate-Based Bio-Composites and Their Potential Applications
title Alginate-Based Bio-Composites and Their Potential Applications
title_full Alginate-Based Bio-Composites and Their Potential Applications
title_fullStr Alginate-Based Bio-Composites and Their Potential Applications
title_full_unstemmed Alginate-Based Bio-Composites and Their Potential Applications
title_short Alginate-Based Bio-Composites and Their Potential Applications
title_sort alginate-based bio-composites and their potential applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397003/
https://www.ncbi.nlm.nih.gov/pubmed/35997455
http://dx.doi.org/10.3390/jfb13030117
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