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Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality

Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-2 virus and has represented one of the greatest challenges humanity has faced in recent years. The virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys,...

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Autores principales: Chávez-Valencia, Venice, Orizaga-de-la-Cruz, Citlalli, Lagunas-Rangel, Francisco Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397016/
https://www.ncbi.nlm.nih.gov/pubmed/35997358
http://dx.doi.org/10.3390/diseases10030053
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author Chávez-Valencia, Venice
Orizaga-de-la-Cruz, Citlalli
Lagunas-Rangel, Francisco Alejandro
author_facet Chávez-Valencia, Venice
Orizaga-de-la-Cruz, Citlalli
Lagunas-Rangel, Francisco Alejandro
author_sort Chávez-Valencia, Venice
collection PubMed
description Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-2 virus and has represented one of the greatest challenges humanity has faced in recent years. The virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys, and intestines, among many others. Although the greatest damage occurs in the lungs, the kidneys are not exempt, and acute kidney injury (AKI) can occur in patients with COVID-19. Indeed, AKI is one of the most frequent and serious organic complications of COVID-19. The incidence of COVID-19 AKI varies widely, and the exact mechanisms of how the virus damages the kidney are still unknown. For this reason, the purpose of this review was to assess current findings on the pathogenesis, clinical features, therapy, and mortality of COVID-19 AKI.
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spelling pubmed-93970162022-08-24 Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality Chávez-Valencia, Venice Orizaga-de-la-Cruz, Citlalli Lagunas-Rangel, Francisco Alejandro Diseases Review Coronavirus disease 2019 (COVID-19) is a disease caused by infection with the SARS-CoV-2 virus and has represented one of the greatest challenges humanity has faced in recent years. The virus can infect a large number of organs, including the lungs and upper respiratory tract, brain, liver, kidneys, and intestines, among many others. Although the greatest damage occurs in the lungs, the kidneys are not exempt, and acute kidney injury (AKI) can occur in patients with COVID-19. Indeed, AKI is one of the most frequent and serious organic complications of COVID-19. The incidence of COVID-19 AKI varies widely, and the exact mechanisms of how the virus damages the kidney are still unknown. For this reason, the purpose of this review was to assess current findings on the pathogenesis, clinical features, therapy, and mortality of COVID-19 AKI. MDPI 2022-08-19 /pmc/articles/PMC9397016/ /pubmed/35997358 http://dx.doi.org/10.3390/diseases10030053 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chávez-Valencia, Venice
Orizaga-de-la-Cruz, Citlalli
Lagunas-Rangel, Francisco Alejandro
Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title_full Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title_fullStr Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title_full_unstemmed Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title_short Acute Kidney Injury in COVID-19 Patients: Pathogenesis, Clinical Characteristics, Therapy, and Mortality
title_sort acute kidney injury in covid-19 patients: pathogenesis, clinical characteristics, therapy, and mortality
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397016/
https://www.ncbi.nlm.nih.gov/pubmed/35997358
http://dx.doi.org/10.3390/diseases10030053
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