Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction

Hyperglycemia and type 2 diabetes (T2D) are caused by failure of pancreatic beta cells. The role of the gut microbiota in T2D has been studied, but causal links remain enigmatic. Obese individuals with or without T2D were included from two independent Dutch cohorts. Human data were translated in vit...

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Detalles Bibliográficos
Autores principales: Scheithauer, Torsten P.M., Herrema, Hilde, Yu, Hongbing, Bakker, Guido J., Winkelmeijer, Maaike, Soukhatcheva, Galina, Dai, Derek, Ma, Caixia, Havik, Stefan R., Balvers, Manon, Davids, Mark, Meijnikman, Abraham S., Aydin, Ömrüm, van den Born, Bert-Jan H., Besselink, Marc G., Busch, Olivier R., de Brauw, Maurits, van de Laar, Arnold, Belzer, Clara, Stahl, Martin, de Vos, Willem M., Vallance, Bruce A., Nieuwdorp, Max, Verchere, C. Bruce, van Raalte, Daniël H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397137/
https://www.ncbi.nlm.nih.gov/pubmed/35984746
http://dx.doi.org/10.1080/19490976.2022.2111951

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