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Decoupling Growth and Production by Removing the Origin of Replication from a Bacterial Chromosome
[Image: see text] Efficient production of biochemicals and proteins in cell factories frequently benefits from a two-stage bioprocess in which growth and production phases are decoupled. Here, we describe a novel growth switch based on the permanent removal of the origin of replication (oriC) from t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397407/ https://www.ncbi.nlm.nih.gov/pubmed/35798328 http://dx.doi.org/10.1021/acssynbio.1c00618 |