Cargando…

Dexmedetomidine Alleviates Neuropathic Pain via the TRPC6-p38 MAPK Pathway in the Dorsal Root Ganglia of Rats

PURPOSE: Neuropathic pain is a chronic intractable disease characterized by allodynia and hyperalgesia. Effective treatments are unavailable because of the complicated mechanisms of neuropathic pain. Transient receptor potential canonical 6 (TRPC6) is a nonselective calcium (Ca(2+))-channel protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Songchao, Yi, Yusheng, Wang, Yanting, Wang, Pei, Zhao, Yang, Feng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397435/ https://www.ncbi.nlm.nih.gov/pubmed/36016537 http://dx.doi.org/10.2147/JPR.S378893

Ejemplares similares

Astragalin Alleviates Neuropathic Pain by Suppressing P2X4-Mediated Signaling in the Dorsal Root Ganglia of Rats
por: Wang, Mengke, et al.
Publicado: (2021)

Electroacupuncture alleviates diabetic neuropathic pain in rats by suppressing P2X3 receptor expression in dorsal root ganglia
por: Fei, Xueyu, et al.
Publicado: (2020)

Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance
por: Liu, Peibin, et al.
Publicado: (2020)

Jinmaitong Alleviates Diabetic Neuropathic Pain Through Modulation of NLRP3 Inflammasome and Gasdermin D in Dorsal Root Ganglia of Diabetic Rats
por: Sun, Qing, et al.
Publicado: (2021)

Effect of TRPV4-p38 MAPK Pathway on Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion
por: Qu, Yu-Juan, et al.
Publicado: (2016)

Differential Transcriptional Profiling of Damaged and Intact Adjacent Dorsal Root Ganglia Neurons in Neuropathic Pain
por: Reinhold, A. K., et al.
Publicado: (2015)

Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain
por: Uttam, Sonali, et al.
Publicado: (2018)

Dorsal Root Ganglia Homeobox downregulation in primary sensory neurons contributes to neuropathic pain in rats
por: Ito, Takaya, et al.
Publicado: (2020)

Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats
por: Matsuka, Yoshizo, et al.
Publicado: (2008)

Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain
por: Zajaczkowska, Renata, et al.
Publicado: (2020)

Dorsal root ganglia: fibromyalgia pain factory?
por: Martínez-Lavín, Manuel
Publicado: (2021)

Integrative multiomic analyses of dorsal root ganglia in diabetic neuropathic pain using proteomics, phospho-proteomics, and metabolomics
por: Doty, Megan, et al.
Publicado: (2022)

MZF1 in the Dorsal Root Ganglia Contributes to the Development and Maintenance of Neuropathic Pain via Regulation of TRPV1
por: Xing, Fei, et al.
Publicado: (2019)

Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age
por: Galbavy, William, et al.
Publicado: (2015)

MAPK Pathways Are Involved in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion
por: Qu, Yu-Juan, et al.
Publicado: (2016)

Upregulation of Na(v)1.6 Mediated by the p38 MAPK Pathway in the Dorsal Root Ganglia Contributes to Cancer-Induced Bone Pain in Rats
por: Lin, Mingxue, et al.
Publicado: (2022)

Human Dorsal Root Ganglia
por: Haberberger, Rainer Viktor, et al.
Publicado: (2019)

Ultrastructure of dorsal root ganglia
por: Haberberger, Rainer Viktor, et al.
Publicado: (2023)

p38 MAPK, microglial signaling, and neuropathic pain
por: Ji, Ru-Rong, et al.
Publicado: (2007)

Na(v)1.7 protein and mRNA expression in the dorsal root ganglia of rats with chronic neuropathic pain★
por: Liu, Chao, et al.
Publicado: (2012)

Melatonin Suppresses Neuropathic Pain via MT2-Dependent and -Independent Pathways in Dorsal Root Ganglia Neurons of Mice
por: Lin, Jia-Ji, et al.
Publicado: (2017)

DNA Microarray Analysis of Differential Gene Expression in the Dorsal Root Ganglia of Four Different Neuropathic Pain Mouse Models
por: Yokoyama, Hiroyuki, et al.
Publicado: (2020)

A Bioinformatics Study of Differentially Expressed Genes in Microarrays of Dorsal Root Ganglia from Rat Models of Neuropathic Pain
por: Wu, Yongle, et al.
Publicado: (2022)

Microencapsulated Schwann cell transplantation inhibits P2X3 receptor expression in dorsal root ganglia and neuropathic pain
por: Zhang, Ya-Ling, et al.
Publicado: (2018)

Inhibition of NKCC1 in spinal dorsal horn and dorsal root ganglion results in alleviation of neuropathic pain in rats with spinal cord contusion
por: Wu, Yao, et al.
Publicado: (2023)

Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling
por: Hervera, Arnau, et al.
Publicado: (2011)

Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Involving the P2Y12 Receptor in the Dorsal Root Ganglia
por: Jia, Tianyu, et al.
Publicado: (2018)

Transcriptome analysis of microRNAs, circRNAs, and mRNAs in the dorsal root ganglia of paclitaxel-induced mice with neuropathic pain
por: Mao, Qingxiang, et al.
Publicado: (2022)

Cancer pain and neuropathic pain are associated with Aβ sensory neuronal plasticity in dorsal root ganglia and abnormal sprouting in lumbar spinal cord
por: Zhu, Yong Fang, et al.
Publicado: (2018)

Electroacupuncture Alleviates Diabetic Neuropathic Pain and Downregulates p-PKC and TRPV1 in Dorsal Root Ganglions and Spinal Cord Dorsal Horn
por: Ma, Yi-qi, et al.
Publicado: (2023)

Neuromodulation of Dorsal Root Ganglia: Chronic Pain Mitigation and Autonomic Implications
por: Ardell, Jeffrey L.
Publicado: (2020)

Mechanisms of Dexmedetomidine in Neuropathic Pain
por: Zhao, Yang, et al.
Publicado: (2020)

Expression of DNA methyltransferases in adult dorsal root ganglia is cell-type specific and up regulated in a rodent model of neuropathic pain
por: Pollema-Mays, Sarah L., et al.
Publicado: (2014)

Efficacy and safety of pulsed radiofrequency as a method of dorsal root ganglia stimulation for treatment of non-neuropathic pain: a systematic review
por: Vuka, Ivana, et al.
Publicado: (2020)

Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons
por: Zaninelli, Tiago H., et al.
Publicado: (2023)

The dorsal root ganglion as a target for neurorestoration in neuropathic pain
por: Estivill-Torrús, Guillermo, et al.
Publicado: (2023)

UNMEDULLATED FIBERS ORIGINATING IN DORSAL ROOT GANGLIA
por: Gasser, Herbert S.
Publicado: (1950)

Advantages of Adult Mouse Dorsal Root Ganglia Explant Culture in Investigating Myelination in an Inherited Neuropathic Mice Model
por: Mo, Yun Jeong, et al.
Publicado: (2022)

The upregulation of EGFR in the dorsal root ganglion contributes to chronic compression of dorsal root ganglions-induced neuropathic pain in rats
por: Wang, Shuo, et al.
Publicado: (2019)

A proteome signature for acute incisional pain in dorsal root ganglia of mice
por: Pogatzki-Zahn, Esther M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hkobevd2c1mo015e67k2trhqe4