Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system

PSENEN/PEN2 is the smallest subunit of the γ-secretase complex, an intramembrane protease that cleaves proteins within their transmembrane domains. Mutations in components of the γ-secretase underlie familial Alzheimer disease. In addition to its proteolytic activity, supplementary, γ-secretase inde...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, Marcel, Kaleem, Abuzar, Oetjen, Sandra, Wünkhaus, Daniela, Binkle, Lars, Schilling, Sandra, Gjorgjieva, Milena, Scholz, Ralf, Gruber-Schoffnegger, Doris, Storch, Stephan, Kins, Stefan, Drewes, Gerard, Hoffmeister-Ullerich, Sabine, Kuhl, Dietmar, Hermey, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397472/
https://www.ncbi.nlm.nih.gov/pubmed/34964690
http://dx.doi.org/10.1080/15548627.2021.2016232

Ejemplares similares

Ejemplares similares