Cargando…

Accelerated Multiphosphorylated Peptide Synthesis

[Image: see text] Preparing phosphorylated peptides with multiple adjacent phosphorylations is synthetically difficult, leads to β-elimination, results in low yields, and is extremely slow. We combined synthetic chemical methodologies with computational studies and engineering approaches to develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Grunhaus, Dana, Molina, Estefanía Rossich, Cohen, Roni, Stein, Tamar, Friedler, Assaf, Hurevich, Mattan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397535/
https://www.ncbi.nlm.nih.gov/pubmed/36032360
http://dx.doi.org/10.1021/acs.oprd.2c00164