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A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture
Optimal treatment of cancer requires diagnostic methods to facilitate therapy choice and prevent ineffective treatments. Direct assessment of therapy response in viable tumor specimens could fill this diagnostic gap. Therefore, we designed a microfluidic platform for assessment of patient treatment...
Autores principales: | Chakrabarty, Sanjiban, Quiros-Solano, William F., Kuijten, Maayke M.P., Haspels, Ben, Mallya, Sandeep, Lo, Calvin Shun Yu, Othman, Amr, Silvestri, Cinzia, van de Stolpe, Anja, Gaio, Nikolas, Odijk, Hanny, van de Ven, Marieke, de Ridder, Corrina M.A., van Weerden, Wytske M., Jonkers, Jos, Dekker, Ronald, Taneja, Nitika, Kanaar, Roland, van Gent, Dik C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397621/ https://www.ncbi.nlm.nih.gov/pubmed/34872965 http://dx.doi.org/10.1158/0008-5472.CAN-21-0799 |
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