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Hypoxia Drives Dihydropyrimidine Dehydrogenase Expression in Macrophages and Confers Chemoresistance in Colorectal Cancer

Colorectal adenocarcinoma is a leading cause of death worldwide, and immune infiltration in colorectal tumors has been recognized recently as an important pathophysiologic event. In this context, tumor-associated macrophages (TAM) have been related to chemoresistance to 5-fluorouracil (5-FU), the fi...

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Detalles Bibliográficos
Autores principales:	Malier, Marie, Gharzeddine, Khaldoun, Laverriere, Marie-Hélène, Marsili, Sabrina, Thomas, Fabienne, Court, Magali, Decaens, Thomas, Roth, Gael, Millet, Arnaud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2021
Materias:	Tumor Biology and Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397622/ https://www.ncbi.nlm.nih.gov/pubmed/34645611 http://dx.doi.org/10.1158/0008-5472.CAN-21-1572

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