Modeling High-Grade Serous Ovarian Carcinoma Using a Combination of In Vivo Fallopian Tube Electroporation and CRISPR-Cas9–Mediated Genome Editing

Ovarian cancer is the most lethal gynecologic cancer to date. High-grade serous ovarian carcinoma (HGSOC) accounts for most ovarian cancer cases, and it is most frequently diagnosed at advanced stages. Here, we developed a novel strategy to generate somatic ovarian cancer mouse models using a combin...

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Detalles Bibliográficos
Autores principales: Teng, Katie, Ford, Matthew J., Harwalkar, Keerthana, Li, YuQi, Pacis, Alain S., Farnell, David, Yamanaka, Nobuko, Wang, Yu-Chang, Badescu, Dunarel, Ton Nu, Tuyet Nhung, Ragoussis, Jiannis, Huntsman, David G., Arseneau, Jocelyne, Yamanaka, Yojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Resource Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397628/
https://www.ncbi.nlm.nih.gov/pubmed/34301761
http://dx.doi.org/10.1158/0008-5472.CAN-20-1518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397628/
https://www.ncbi.nlm.nih.gov/pubmed/34301761
http://dx.doi.org/10.1158/0008-5472.CAN-20-1518

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